Dioscorine is one of few alkaloids to possess an isolated isoquinuclide nucleus that is not part of a condensed ring system, unlike catharanthine or other indole alkaloids.
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The residue from the distillation of high-temperature coal tar, primarily a complex mixture of three or more membered condensed ring aromatic hydrocarbons, was listed on 28 October 2008 as a substance of very high concern by the European Chemicals Agency.
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